Chronic inflammation and abdominal obesity can together cause and worsen several diseases. Metabolically active abdominal fat, especially visceral fat, can create inflammatory chemicals, causing chronic low-grade inflammation.
Adipose tissue, especially visceral fat, releases pro-inflammatory compounds such cytokines (e.g., interleukin-6, tumor necrosis factor-alpha) and adipokines (e.g., leptin). These chemicals can cause and maintain systemic inflammation.
Linking Insulin Resistance to Abdominal Fat: Cells become insulin-resistant when belly fat increases. Insulin resistance causes metabolic dysfunction and inflammation.
Metabolic Syndrome Parts: Chronic inflammation is central to metabolic syndrome, which includes abdominal obesity, insulin resistance, elevated blood pressure, and abnormal cholesterol levels.v
Cardiovascular Diseases: Atherosclerosis: Chronic inflammation contributes to plaque formation in artery walls. Hypertension and dyslipidemia are linked to abdominal fat.
Type 2 Diabetes: Insulin Dysfunction Type 2 diabetes can result from abdominal fat-induced inflammation that disrupts insulin signaling.
Respiratory Disorders: - Inflammatory Lung Conditions: - Abdominal obesity is linked to asthma and obstructive sleep apnea. Chronic inflammation may worsen these illnesses.
To control and prevent the effects of chronic inflammation and belly obesity on health, people should take a comprehensive approach to health, including frequent medical checkups.
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